Webinar: Innovative preclinical research using humanized NSG™ mice

Innovative Preclinical Research Using Humanized NSG™ Mice (2/20/2014)

The NOD scid gamma mouse uniquely supports the engraftment of human hematopoietic cells, enabling the creation of "humanized" NSG (hNSG) mice. These mice serve as the state-of-the art platform for studying immunobiology, infectious diseases, graft-versus-host disease, and transplantation.

The NOD scid gamma mouse uniquely supports the engraftment of human hematopoietic cells, enabling the creation of “humanized” NSG™ (hNSG) mice. These mice serve as the state-of-the art platform for studying immunobiology, infectious diseases, graft-versus-host disease and transplantation.

This video highlights the superior capabilities of the NSG™ mouse:

  • Key genetic components rendering NSG™ mice immunodeficient
  • The superiority of the NSG™ mouse as a platform for humanization
  • Advantages and considerations for specific NSG™ humanization protocols
  • Data demonstrating preclinical applications of hNSG mice
  • How to obtain humanized NSG™ from JAX® In Vivo Pharmacology Services
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Whitepaper: Humanized Mice for Immuno-Oncology

NSG™ mice are a proven host for engraftment of human tumors or establishment of human immunity following hematopoietic stem cell transplantation.

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