Webinar: Innovative preclinical research using humanized NSG™ mice
Innovative Preclinical Research Using Humanized NSG™ Mice (2/20/2014)
The NOD scid gamma mouse uniquely supports the engraftment of human hematopoietic cells, enabling the creation of "humanized" NSG (hNSG) mice. These mice serve as the state-of-the art platform for studying immunobiology, infectious diseases, graft-versus-host disease, and transplantation.
The NOD scid gamma mouse uniquely supports the engraftment of human hematopoietic cells, enabling the creation of “humanized” NSG™ (hNSG) mice. These mice serve as the state-of-the art platform for studying immunobiology, infectious diseases, graft-versus-host disease and transplantation.
This video highlights the superior capabilities of the NSG™ mouse:
- Key genetic components rendering NSG™ mice immunodeficient
- The superiority of the NSG™ mouse as a platform for humanization
- Advantages and considerations for specific NSG™ humanization protocols
- Data demonstrating preclinical applications of hNSG mice
- How to obtain humanized NSG™ from JAX® In Vivo Pharmacology Services