On-Demand: CRISPR/Cas-mediated genome engineering in mice 

CRISPR/Cas Mediated Genome Engineering in Mice (3/27/2014)

Targeting multiple genes in one generation? Systematically modulating individual components of a system in a few years rather than decades? The promises of precise, combinatorial, efficient methods for genomic engineering are exciting. The CRISPR/Cas technology applied to mouse genetic engineering could quickly advance scientific understanding of disease mechanisms by allowing researchers to ask complex questions and find answers much faster than with traditional gene targeting approaches. During this webinar, Dr. Haoyi Wang, one of the developers of this revolutionary technology will share how CRISPR/Cas has been used successfully in mice to generate endogenous knock-in alleles, conditional (“floxed”) mutations, as well as multiple mutations in a single generation.

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