Introduction to Mice for Cancer Immunotherapy

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The mammalian immune system has developed surveillance mechanisms that can detect cancerous cells. However, successful tumor cells have evolved strategies to evade detection. Current therapeutic strategies focus on improving cancer cell recognition and tumor elimination. Mouse models have been instrumental in the development of these therapies, including both immunocompetent and immunodeficient mice. This presentation will focus on the following topics:

  • Types of cancer immunotherapeutics that have been characterized and validated in mouse models
  • Cutting-edge humanized mouse models that are the next generation platform for immuno-oncology

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Sep 26

2017