Oct 25 Virtual | Impacts of Sleep and Circadian Biology on Alzheimer's Disease and Aging

Virtual | Impacts of Sleep and Circadian Biology on Alzheimer's Disease and Aging

Please contact the event organizer for more information

About

Join us in attending the virtual instance of a new interdisciplinary 3.5-day conference that will focus on the emerging and complex relationships between aging, sleep and circadian rhythm, and Alzheimer’s disease (AD) progression. This annual, NIA-supported conference will focus on recent research advances that employ cutting-edge genetic, genomic, and computational biology approaches and technologies and that have enabled more precise descriptions of molecular and cellular changes that occur and that integrate these three biological processes (aging, sleep/circadian rhythm, and AD progression).

This course is perfect for: graduate students, postdoctoral fellows, and junior and senior investigators from the fields of aging and Alzheimer's disease, neurodegeneration, genetics of sleep/circadian biology, and computational biology.

This virtual instance of this course will feature:

3.5 days of live-streamed morning lectures taking place from 8:00 am – 12:00 pm EDT

Lectures will introduce trainees to the fundamentals of sleep/circadian biology and advanced computational approaches in genetics and genomics.

Recordings of the live lectures will be made available within 72 hours of airing and will be accessible to registered virtual participants for asynchronous viewing until November 30, 2021.

Virtual participants will be able to ask questions using a Q&A feature.

We look forward to seeing you in-person at this conference in future years!

Research reported in this publication was supported by the National Institutes of Health and the National Institute on Aging under Award Number R13AG072861 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Schedule

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12:00 PM

Day 1

Monday, October 25^th

8:00 – 8:45 am
Keynote Lecture: Molecular Mechanism of the Circadian Clock
Joseph Takahashi, Ph.D., UT Southwestern

8:45 – 9:30 am
A Mechanism for Sleep Fragmentation During Aging
Luis de Lecea, Ph.D., Stanford University

9:30 – 9:45 am
Break

9:45 – 10:30 am
Advanced Mouse Populations
Gary Churchill, Ph.D., The Jackson Laboratory

10:30 – 11:15am
GWAS for Chronotype and Sleep Traits
Richa Saxena, Ph.D., Massachusetts General Hospital

11:15 am – 12:00 pm
Genetics of Human Circadian Variation
Louis Ptacek, M.D., University of California, San Francisco

12:00 PM

Day 2

Tuesday, October 26^th

8:00 – 8:45 am
Influence of Circadian Clocks on Neurodegeneration
Erik Musiek, M.D., Ph.D., Washington University School of Medicine in St. Louis

8:45 – 9:30 am
Genetics of Alzheimer's Disease: Toward a Mechanistic Understanding of Disease
Alison Goate, D.Phil., Icahn School of Medicine at Mount Sinai

9:30 – 9:45 am
Break

9:45 – 10:30 am
Aligning New Mouse Models of Alzheimer's Disease with Human Studies
Gregory Carter, Ph.D., The Jackson Laboratory

10:30 – 11:15am
The MODEL-AD Consortium: Creating Improved Preclinical Models for LOAD
Gareth Howell, Ph.D., The Jackson Laboratory

11:15 am – 12:00 pm
Modeling Sleep Disruption in Genetically Diverse AD Mouse Models
Catherine Cook Kaczorowski, Ph.D., The Jackson Laboratory

12:00 PM

Day 3

Wednesday, October 27^th

8:00 – 8:45 am
Keynote Lecture: Systems Genetics of Sleep
Paul Franken, Ph.D., Universite de Lausanne

8:45 – 9:30 am
Tools to Decipher Biology at Single Cell Resolution
Paul Robson, Ph.D., The Jackson Laboratory

9:30 – 9:45 am
Break

9:45 – 10:30 am
Single Cell Approaches to Identify Reproducible Cell Type Changes in AD
Vilas Menon, Ph.D., Columbia University

10:30 – 11:15am
Insights from Clock Genomics
John Hogenesch, Ph.D., Cincinnati Children’s Hospital