The annual Cancer Short Course remains the signature cancer training program at JAX and is strategically aligned with the ongoing Workshop on Techniques in Modeling Human Cancer in Mice. The program purposefully provides a broad survey of the cancer research and experimental modeling from systems and computational genetics, to the tumor microenvironment and tumor progression, to inflammation and immunotherapy. The immersive, residential approach of the Cancer Short Course provides rich and extensive content and skills for up to 50 trainees.
Please contact the event organizer for more information
Aug 15 - 24
2019
Unlike a semester-long graduate course or an academic seminar series spread across a full year or more, the course delivers a large amount of material into an intensive training period. The program is 70% seminar-based and 30% workshop-based, including computational workshops. The program is designed around a daily schedule that balances lectures, hands-on workshops, informal meetings with faculty, and evening seminar and poster sessions. Over eight days, participants interact directly with faculty, JAX Cancer Center scientists, patient advocates and medical oncologists to gain broad exposure and knowledge as it relates to human cancer.
It is held in a retreat-like setting and is limited to 50 participants to ensure a supportive, interactive learning atmosphere.
Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under Award Number R25CA122819. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
4:00 AM |
12:00pm-3:00pm Arrival and check in
3:00pm-4:00pm Student Introductions
4:00pm-5:00pm Inflammation and Cancer: Good Cells Behaving Badly Lisa M. Coussens, Knight Cancer Institute
5:00pm-6:00pm TBD Mario Sznol, Yale University
6:00pm-7:00pm Happy Hour
7:00pm Dinner |
4:00 AM |
8:30 am – 9:30 am Genomic Biology of Triple Negative Breast Cancer Edison Liu, M.D., President & CEO, The Jackson Laboratory
9:30 am – 10:30 am Disseminated Tumor Cell Dormancy and Therapeutic Resistance Cyrus Ghajar, Ph.D., Fred Hutchinson Cancer Research Center
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Role of Adult Stem Cell Niches and Primed Pluripotency Programs in Early DCC Dormancy Julio A. Aguirre-Ghiso, MSc, Ph.D., Icahn School of Medicine at Mount Sinai
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm Tumor Exosomes and Exomeres Promote Metastasis and Systemic Disease Haiying Zhang, Ph.D., Cornell Medical College
2:00 pm – 5:00 pm Optional Workshop: Biomethods Kristen Cough, B.S., LVT, LATg, The Jackson Laboratory
5:30 pm – 7:00 pm Happy Hour, Free, or Hike
7:00 pm – 9:00 pm Gala Dinner, Regency |
4:00 AM |
8:30 am – 9:30 am Induction of Adaptive Immunity Stephanie Eisenbarth, M.D., Ph.D., Yale School of Medicine
9:30 am – 10:30 am Adam Williams, Ph.D. The Jackson Laboratory
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Exploiting Metabolic Stress in Cancer Treatments Dr. Tak W. Mak, OC, PhD, DSc. (Hons), FRSC, FRS, University Health Network
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm Integrative Biology and Omics of T Cell-Dendritic Cell Encounters Bernard Malissen, PhD, CIML
2:00 pm – 3:00 pm Break
3:00 pm – 3:30 pm Imaging the Tumor Microenvironment – Many Colors, Lots of Information Ronald N. Germain, M.D., Ph. D., NIAD, NIH
3:30pm – 6:30 pm Optional Hike with Faculty
Free Evening – Dinner on your own
|
4:00 AM |
August 18 8:30 am – 9:30 am Myeloid Cell Determinants of Antitumor Immunity Miriam Merad, M.D., Ph.D., Icahn School of Medicine at Mount Sinai
9:30 am – 10:30 am Innate Lymphoid Cells in Biology Marco Colonna, M.D., Ph.D., Washington University School of Medicine
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Immunologic Checkpoint Blockade: Dissecting Mechanisms and Next Steps Jedd Wolchock, M.D., Ph.D., Memorial Sloan Kettering Cancer Center
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm Mechanisms of Autoimmunity and Autoinflammation Virginia Pascual, M.D., Weill Cornell Medicine
2:00 pm – 3:00 pm Influence of the Microbiota on Local and Systemic Immunity Dan R. Littman, M.D., Ph.D., Howard Hughes Medical Institute, New York University School of Medicine
3:00 pm – 3:30 pm Break
3:30 pm – 4:30 pm Reverse Translational Studies to Guide Anti-PD-1 Cancer Combination Strategies in the Clinic Elaine Pinheiro, Ph.D., In Vivo Pharmacology, Merck
4:30 pm – 5:30 pm Q&A with faculty
6:00 pm – 7:00 pm Happy Hour
7:00 pm Dinner, Highseas
|
4:00 AM |
8:30 am – 9:30 am Fundamentals of Gemomics and Immunogenics Elaine R. Mardis, PhD, FAACR, The Institute for Genomic Medicine-Nationwide Children’s Hospital
9:30 am – 10:30 am Alternative RNA Splicing Defects in Cancer: Molecular and Therapeutic Insights From Model Systems Olga Anczukow, Ph.D., The Jackson Laboratory
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Understanding and Targeting Spliceosomal Gene Mutations in Cancer Omar Abdel-Wahab, M.D., Memorial Sloan Kettering Cancer Center
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm Jacques Banchereau, Ph.D., The Jackson Laboratory
2:00 pm – 3:00 pm Nicholas Navin, Ph.D., University of Texas MD Anderson Cancer Center
3:00 pm – 6:30 pm Optional Workshop: Single Cell Paul Robson, Ph.D., The Jackson Laboratory Nicholas Navin, Ph.D., University of Texas MD Anderson Cancer Center
7:00 pm – 9:00 pm Poster Session & Buffet Dinner, Regency |
4:00 AM |
8:30 am – 9:30 am Clonal Hematopoiesis as a Predisposition Condition in Acute Myeloid Leukemia Jennifer Trowbridge, Ph.D., The Jackson Laboratory
9:30 am – 10:30 am Opposing Roles of Interferon and Pattern Recognition Receptor Signaling in Cancer and Cancer Immunotherapy Andy Minn, M.D., Ph.D., University of Pennsylvania
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Ralph Scully, Ph.D., Medicine, Harvard Medical School
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 3:00 pm Optional Workshop: Xenografting Techniques (Subcutaneous and Kidney Capsule) Bonnie Lyons, D.V.M., The Jackson Laboratory
1:00 pm – 3:00 pm Optional Workshop: Data Analysis and Resources for Patient-Derived Cancer Models Jeff Chuang, Ph.D., The Jackson Laboratory
3:00 pm – 3:30 pm Break
3:30pm – 5:30 pm Optional Workshop: Carol Bult, Ph.D., The Jackson Laboratory
6:00 pm – 7:00 pm Happy Hour
7:00 pm – 9:00 pm MGI Dinner, Regency |
4:00 AM |
8:30 am – 9:30 am Modeling Anti-Cancer Immune Responses in Mice Marcus Bosenberg, M.D., Ph.D., Yale
9:30 am – 10:30 am Matthew Krummel, Ph.D., University of California, San Francisco
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Ching Lau, M.D., Ph.D., The Jackson Laboratory
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00pm Normal and Neoplastic Stem Cells Presented via Webex Irving Weissman, M.D., Stanford University
2:00 pm – 4:30 pm Optional Workshop: Metabolic and Immune Control of Liver Tumorigenesis Michael Karin, Ph.D., University of California, San Diego
4:30 pm – 5:30 pm Katerina Politi, Ph.D., Yale
5:30 pm – 6:00 pm CIPHE Contribution to Genomic and Immunophenomic World-wide Coordinated Programs Ana Zarubica, Ph.D., Centre d'Immunophenomique
6:15 pm – 7:00 pm Happy Hour
7:00 pm Dinner, Highseas
|
4:00 AM |
8:30 am – 9:30 am Pier Paolo Pandolfi, M.D., Ph.D., Harvard Medical School
9:30 am – 10:30 am Human Pancreatic Cancer insights from Model Systems David Tuveson, M.D., Ph.D., Cold Spring Harbor Laboratory
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Q & A Models
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm Emerging Models of Humanized Mice for Cancer Research Lenny Shultz, Ph.D., The Jackson Laboratory
2:00 pm – 3:00 pm Modeling Human T Cell Selection and Type 1 Diabetes Megan Sykes, M.D., Columbia University
3:00 pm – 3:30 pm Break
3:30 pm – 4:30 pm Karolina Palucka, M.D., Ph.D., The Jackson Laboratory
4:30 pm – 5:30 pm Optional Workshop: Humanzied Mice
5:30pm Free Evening – Dinner on your own
|
4:00 AM |
8:30 am – 9:30 am Reprogramming the Tumor Microenvironment to Enhance Cancer Treatment: Bench to Bedside Rakesh K. Jain, Ph.D., Harvard Medical School, Massachusetts General Hospital 9:30 am – 10:30 am The Anatomy of the Anti-Tumor Immune Response Amanda Lund, Ph.D., Oregon Health & Science University
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Structure and Function of Mammalian SWI/SNF Chromatin Remodeling Complexes in Human Cancer Cigall Kadoch, Ph.D., Harvard Medical School, Dana-Farber Cancer Institute, Broad Institute
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm The Microbiome, Inflammation and Cancer Julia Oh, Ph.D., The Jackson Laboratory
2:00 pm – 3:30 pm Optional Workshop: Mark Adams, Ph.D., The Jackson Laboratory
2:00 pm – 5:00 pm Necropsy James Miller, The Jackson Laboratory
3:30pm – 4:30 pm Q&A George Weinstock, Ph.D., The Jackson Laboratory
7:00 pm – 9:00 pm Lobster Bake, Bar Harbor Lobster Bakes
|
4:00 AM |
8:30 am – 9:30 am Zebrafish Models of Human Cancer for Drug Discovery and Chemical Biology A Thomas Look, MD, Dana-Farber Cancer Institute, Harvard Medical School
9:30 am – 10:30 am Use of Animal Models to Design Strategies to Overcome Resistance to Immune Checkpoint Blockade Taha Merghoub, Ph.D.
10:30 am – 11:00 am Break
11:00 am – 12:00 pm Laura Reinholdt, Ph.D., The Jackson Laboratory
12:00 pm – 1:00 pm Lunch, Roscoe’s
1:00 pm – 2:00 pm Poster Prize
2:00 pm Adjourn
|
Provided lodging will be at the gorgeous Highseas Conference Center, a Georgian style mansion built in 1912, overlooking the entrance to Frenchman’s Bay and adjacent to Acadia National Park. This casual, dormitory-style housing consists of shared bedrooms and bathrooms. Breakfast, lunch, dinner, and snacks will be provided at Highseas, including a lobster and steak dinner one night during the event. Wireless internet access is provided throughout the building and laundry facilities are available on site.
Highseas cannot accommodate families or pets. Please refer to the Bar Harbor Chamber of Commerce for lodging alternatives available
Air
Bar Harbor is serviced by two airports:
Car
Bar Harbor is approximately 5 hours by car from the greater Boston area. Rental cars are available from Hertz at either nearby airport. Additionally, there is a free Island Explorer bus system which can be used around the island and the national park.
Rideshare options like Uber or Lyft are not commonly available.
Additional Area Information:
Associate Member in Human Oncology & Pathogenesis Program
Professor and Deputy Director, JAX Genomic Medicine
Professor
Associate Professor
Professor of Dermatology and Pathology
Professor
Robert Rock Belliveau, M.D. Endowed Professor of Pathology
Associate Professor of Laboratory Medicine & Immunobiology
Chief, Laboratory of Systems Biology, Chief, Lymphocyte Biology Section
Assistant Member, Public Health Sciences Division/Translational Research Program
Andrew Werk Cook Professor of Radiation Oncology; Director, Steele Laboratory
Associate Professor, Department of Pediatric Oncology
Distinguished Professor of Pharmacology, Ben and Wands Hildyard Chair for Mitochondrial and Metabolic Diseases, American Cancer Society Research Professor
Sr. Director, In Vivo Pharmacology & Clinical Lab Services JW In Vivo Services-Core
Professor
Professor
Skirball Institute, Helen L. and Martin S. Kimmell Professor of Molecular Immunology, Department of Pathology, Professor, Department of Microbiology
Professor, President Emeritus and Honorary Fellow
Associate Professor
Associate Veterinarian
Senior Staff Scientist, Professor
Director of Centre d'Immunophénomique
Co-Executive Director of the Institute for Genomic Medicine
Mount Sinai Chair Professor in Cancer Immunology and Director of the Precision Immunology Institute
Associate Laboratory Member
Necropsy Technologist II
Associate Professor of Radiation Oncology
Associate Professor
Associate Professor
Director, Cancer Center & Cancer Research Institute at Beth Israel Deaconess Medical Center, Chief, Division of Genetics, Department of Medicine, BIDMC, George C. Reisman Professor of Medicine and Professor of Pathology
Director, Gale and Ira Drukier Institute for Children’s Health
Director
Associate Professor
Associate Professor
Associate Professor
Professor
Associate Vice President
Chief Medical Officer, JAX; Medical Director, MCGI
Professor of Medicine, Harvard Medical School
Professor
Professor & Director, Columbia Center for Translational Immunology
Professor, Internal Medicine
Professor, The Dattels Family Chair
Director of Cold Spring Harbor Laboratory Cancer Center and Professor
Director, Institute for Stem Cell Biology and Regenerative Medicine
Chief, Melanoma and Immunotherapeutics Service, Lloyd J. Old Chair for Clinical Investigation
Chief Operation Officer
Assistant Professor of Cell & Developmental Biology in Pediatrics
Professor, Director, JAX Cancer Center, Edison T. Liu Endowed Chair in Cancer Research
Professor, Knowlton Family Chair
Professor of Pediatrics
Professor and Chairwoman, Dept of Cell, Developmental, and Cancer Biology