Whole Genome Sequencing

What are the assay characteristics?

  • The JAX COVID-19 Whole Genome Sequencing (WGS) Assay test system is an amplicon-based NGS assay, with 98 amplicons designed to amplify SARS-CoV-2 -virus-specific amplicons utilizing the Illumina COVIDSeq next generation sequencing (NGS) assay.

What are possible test results, and what do they mean?

  • Positive: Positive for SARS-CoV-2. Pangolin Lineage, NextStrain Clade assignment, CDC classification and detected amino acid deletions and substitutions of isolate are included in report.
  • Failed: Insufficient sample quantity or quality to generate reportable sequencing results.
  • If you are unsure of or have any questions regarding the sequencing portion of your results, please contact your medical provider.
  • CDC Page on Variant Classifications and Definitions: https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html

What if my personal information on the report is wrong?

  • Please reach out to your provider to alert them of the error. They will be able to work with us to create a corrected report that will be sent back to your provider.