Jackson Laboratory

体内代谢药理学

我们为肿瘤学、免疫学和神经生物学领域的基础研究和新疗法的发展提供最终解决方案; 为您的研究提供最可靠、有创新性的临床前人源化动物模型及其功能有效性评估服务.

micetech@jax.org | + 1.207.288.5845

Oncology

We specialize in the production of innovative oncology research models including PDX models and compound evaluation using PDX or cell line xenograft models, and efficacy testing of cancer immunotherapeutics.

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Immunology

Our preclinical testing facility specializes in the production of cutting-edge immunological research models including humanized CD34⁺and PBMC mice and compound evaluation of standardized preclinical models of autoimmune and inflammatory diseases.

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Neurobiology

We offer a diverse set of efficacy – testing capabilities and compound evaluation in the areas of muscular dystrophy and neurodegeneration.

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Patient-Derived Xenograft (PDX) Models

Over 300 patient-derived xenograft (PDX) tumors are available for engrafting into immunocompromised NSG™ mice for shipment to your facility or use in JAX-directed preclinical efficacy studies.

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Humanized Mice

Humanized mouse models are powerful tools for studying cancer, inflammatory and infectious disease, and hematopoiesis. We provide fast access to study-ready cohorts.

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Therapeutic Drug Evaluation Services

We evaluate the pharmacokinetics, bioavailability and efficacy of therapeutic monoclonal antibodies in vivo, using unique JAX-generated FcRn-humanized models.

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