ActionSeq™

Molecular profiling of tumors to identify mutations
that accumulate in cancer cells.

jaxmoleculardx@jax.org | 1.860.837.2320

Gene List

212 Gene panel (SNPs, CNVs and micro InDels):

ABL1, ABL2, AIM2, AKT1, AKT2, AKT3, ALK, APC, AR, ARAF, ARID1A, ATM, ATR, AURKA, AURKB, AXIN1, AXL, BAP1, BARD1, BCL2, BIRC5 (Survivin), BRAF, BRCA1, BRCA2, BRD3, BRD4, BRIP1, BTK, CALR, CBL, CCND1, CCND2, CCND3, CCNE1, CD274, CD79A, CD79B, CDK12, CDK4, CDK6, CDK8, CDKN1A, CDKN2A, CHEK1, CHEK2, CREBBP, CRKL, CSF1R, CSF3R, CTNNB1, CXCR4, DDR1, DDR2, DDX11, DNMT3A, DNMT3B, DYRK1B, EGFR, EP300, EPHA2, EPHB4, ERBB2, ERBB3, ERBB4, ERG, ESR1, ETV1, EZH1, EZH2, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCL, FANCM, FBXW7, FES, FGF19, FGF3, FGFR1, FGFR2, FGFR3, FGFR4, FH, FLCN, FLT1, FLT3, FLT4, FRK, FRS2, GLI1, GLI2, GNA11, GNAQ, GNAS, GRM3, HGF, HRAS, HSP90AA1, ID1, ID2, ID3, IDH1, IDH2, IGF1R, IKBKE, IL7R, IRS2, JAK1, JAK2, JAK3, JUN, KDM4C, KDR, KEAP1, KIAA1524 (CIP2A), KIT, KRAS, LTK, MAP2K1, MAP2K2, MAP3K9, MAPK1, MCL1, MDM2, MDM4, MEN1, MET, MPL, MRE11 (MRE11A), MSH2, MSH6, MST1R (RON), MTOR, MYC, MYCL, MYCN, MYD88, NBN, NCOA3, NF1, NF2, NFE2L2, NISCH, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NRAS, NTRK1, NTRK2, NUAK2, PAK1, PALB2, PDGFRA, PDGFRB , PDPK1, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIM1, PLK1, POLB, POLR2A, PPARG, PPM1D, PPP2R1A, PPP2R1B, PRKAA1, PTCH1, PTEN, PTK2(FAK), PTPN11, PTPRB, RAD50, RAD51, RAD51C, RAD51D, RAF1, RARA, RB1, RET, RHEB, RICTOR, RIT1, RNF43, ROS1, RSPO2, RSPO3, SEM1 (SHFM1), SMARCB1, SMO, SRC, STAT3, STAT5A, STAT5B, STK11(LKB1), SYK, TGFBR2, TNK2 (ACK1), TP53, TP63, TSC1, TSC2, TTK (MPS1), VEGFA, VHL