ActionSeq™

Molecular profiling of tumors to identify mutations
that accumulate in cancer cells.

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Gene List

212 Gene panel (SNPs, CNVs and micro InDels):

ABL1, ABL2, AIM2, AKT1, AKT2, AKT3, ALK, APC, AR, ARAF, ARID1A, ATM, ATR, AURKA, AURKB, AXIN1, AXL, BAP1, BARD1, BCL2, BIRC5 (Survivin), BRAF, BRCA1, BRCA2, BRD3, BRD4, BRIP1, BTK, CALR, CBL, CCND1, CCND2, CCND3, CCNE1, CD274, CD79A, CD79B, CDK12, CDK4, CDK6, CDK8, CDKN1A, CDKN2A, CHEK1, CHEK2, CREBBP, CRKL, CSF1R, CSF3R, CTNNB1, CXCR4, DDR1, DDR2, DDX11, DNMT3A, DNMT3B, DYRK1B, EGFR, EP300, EPHA2, EPHB4, ERBB2, ERBB3, ERBB4, ERG, ESR1, ETV1, EZH1, EZH2, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCL, FANCM, FBXW7, FES, FGF19, FGF3, FGFR1, FGFR2, FGFR3, FGFR4, FH, FLCN, FLT1, FLT3, FLT4, FRK, FRS2, GLI1, GLI2, GNA11, GNAQ, GNAS, GRM3, HGF, HRAS, HSP90AA1, ID1, ID2, ID3, IDH1, IDH2, IGF1R, IKBKE, IL7R, IRS2, JAK1, JAK2, JAK3, JUN, KDM4C, KDR, KEAP1, KIAA1524 (CIP2A), KIT, KRAS, LTK, MAP2K1, MAP2K2, MAP3K9, MAPK1, MCL1, MDM2, MDM4, MEN1, MET, MPL, MRE11 (MRE11A), MSH2, MSH6, MST1R (RON), MTOR, MYC, MYCL, MYCN, MYD88, NBN, NCOA3, NF1, NF2, NFE2L2, NISCH, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NRAS, NTRK1, NTRK2, NUAK2, PAK1, PALB2, PDGFRA, PDGFRB , PDPK1, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIM1, PLK1, POLB, POLR2A, PPARG, PPM1D, PPP2R1A, PPP2R1B, PRKAA1, PTCH1, PTEN, PTK2(FAK), PTPN11, PTPRB, RAD50, RAD51, RAD51C, RAD51D, RAF1, RARA, RB1, RET, RHEB, RICTOR, RIT1, RNF43, ROS1, RSPO2, RSPO3, SEM1 (SHFM1), SMARCB1, SMO, SRC, STAT3, STAT5A, STAT5B, STK11(LKB1), SYK, TGFBR2, TNK2 (ACK1), TP53, TP63, TSC1, TSC2, TTK (MPS1), VEGFA, VHL

Genetic Drift

Clinical Knowledgebase

JAX-Clinical Knowledgebase (CKB) is a powerful tool for interpreting complex genomic profiles, and represents a valuable resource for clinicians and translational and clinical researchers around the world.

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CTP

Cancer Treatment Profile™

This test provides analysis of 358 cancer-associated genes through next-generation sequencing. The panel assesses all identified functional variants for clinical relevance, based on associations in the biomedical literature with response or resistance to FDA-approved targeted therapies or new drugs in development.

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New CRISPR

ActionSeq™

ActionSeq™ is a targeted panel of 212 cancer related genes analyzed using next-generation sequencing. The panel assesses all identified functional variants for clinical relevance, based on associations in the biomedical literature with response or resistance to FDA-approved targeted therapies. 

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