Karen B. Avraham, Ph.D.

Principle investigator, Dept. of Human MolecularSackler School of Medicine Tel Aviv University

Professor Karen B. Avraham is the incumbent of the Drs. Sarah and Felix Dumont Chair for Research of Hearing Disorders at Tel Aviv University, a faculty member of the Department of Human Molecular Genetics and Biochemistry, and Vice Dean at the Sackler Faculty of Medicine. Born in Canada and raised in the US, Dr. Avraham received her B.A. from Washington University, U.S., Ph.D. at the Weizmann Institute of Science, Israel and post-doctoral training at the National Cancer Institute, Maryland, US. Prof. Avraham moved to Israel to begin her position at Tel Aviv University in 1996. Dr. Avraham’s research has centered on the discovery of disease genes, focusing on hereditary deafness. Her group is asking the questions: (1) What are the genes that lead to hearing loss and how are they involved in normal function of the inner ear? (2) How does regulation of gene expression govern the pathways that determine inner ear function and how do alterations in regulation, on a genetic and epigenetic level, contribute to the pathology of deafness? Dr. Avraham leads the effort in exome sequencing for the discovery of disease genes to identify variants that are relevant for the Middle Eastern hearing-impaired population. Her group has demonstrated that non-coding RNAs are essential for development and function of inner ear hair cells in vertebrates.

Dr. Avraham was awarded the Bruno Memorial Prize, the TEVA Prize for Groundbreaking Research in the Field of Rare Diseases, and the Teva Founders Prize on Breakthroughs. She is now President of the Scientific Committee of Agir Pour Audition, a foundation for hearing health based in Paris; of ILANIT, the federation of all the Israel societies for experimental biology; and the Israel Society for Auditory Research. She is a board/council member of I-CORE – Israeli Center of Research Excellence, the Human Genome Organization (HUGO) and of the European Molecular Biology Organization (EMBO) and elected member of the Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum (CORLAS).
Sessions
Sep 20 8:30 AM Tuesday, September 20, 2016 8:30am Lecture: Deafness genes in humans    
9:15am    Lecture: Deafness genes in mouse mutants and mouse models in the IMPC    
10:00am    Coffee break    
10:15am    Inner ear development    
11:00am    Inner ear development: Planar cell polarity
12:00pm    Lunch at Highseas    
12:45pm    Van shuttle to Research Lab    
1:00pm    5 hour Teaching Lab workshop(s)    Behavior, ABR, VsEP, DPOAE, tympanometry
6:00pm    Van shuttle to Highseas    
6:30pm    Dinner at High Seas    
7:00pm free evening