Mike Bowl

Mike Bowl, DPhil

Principal Research FellowUCL Ear Institute

Dr. Bowl is a Principal Research Fellow at the UCL Ear Institute, UK. He earned his BSc (Medical Biochemistry, 1998) and MPhil (Immunology and Oncology, 1999) from the University of Birmingham, and completed his DPhil (Molecular Endocrinology, 2003) at the University of Oxford, where he continued as a post-doctoral scientist until 2009. While at Oxford he was a Junior Research Fellow at Linacre College (2006-2008). In 2010, Dr. Bowl joined the MRC Harwell Institute as the Team Leader for Sensorineural Hearing Loss and in 2020 he joined the UCL Ear Institute. Dr. Bowl and his team utilize the mouse for the study of genes required for hearing and to determine the cochlear pathologies that result from their loss, with a longer-term view that increased understanding of the molecular pathobiology of disease will lead to therapeutic opportunities. While based at the MRC Harwell Institute, he was heavily involved in large-scale phenotype- and gene-driven programmes aimed at uncovering gene function in the mouse. Using these approaches he and his team continue to identify and characterize novel genes required for mammalian hearing function, and to elaborate upon our understanding of the genetic pathways involved in sensory hair cell maturation, function and maintenance, with a particular focus on age-related hearing loss (ARHL).

Sep 19 8:30 AM Monday, September 19, 2016 8:30am    Topic: Mouse genetics, nomenclature, and MGI
9:15am    Topic Genetic background and age-related effects
10:00am    Coffee break    
10:30am Topic: Microscopy in inner ear research
11:15am Lecture: New programs and resources, KOMP, resources for gene expression
12:00pm Lunch     
1:00pm Student poster presentations    
2:30pm Group photo    
2:45pm Van shuttle to Research Lab    
3:15pm Biomethods training    
4:30pm Jackson Lab tour     
5:00pm Visit Electron MIcroscopy Service and SEM demo      
6:00pm Van shuttle to Highseas    
6:30pm Dinner     
7:30pm New technologies: CRISPR-Cas genome editing
8:15pm New technologies: CRISPR-Cas applied to hearing research