Alexander Nikitin

Alexander Nikitin, M.D., Ph.D.

Professor of Pathology; Leader, Cornell Stem Cell ProgramCornell University

Alexander Nikitin, M.D., Ph.D. is Professor of Pathology in the Department of Biomedical Sciences of Cornell College of Veterinary Medicine, Leader of the Cornell Stem Cell Program, and Director of the Cornell Training Program in Stem Cell Research at the Cornell University. Dr. Nikitin has over 30 years of experience in comparative pathology, cancer and stem cell research, with studies of the female and male reproductive tracts being the most significant parts of his activities during past 20 years. In that area, his laboratory established the first autochthonous mouse model of high-grade serous ovarian carcinoma, and new mouse models of metastatic prostate cancer and serous endometrial carcinoma. Dr. Nikitin's laboratory also identified novel cancer-prone cell populations in epithelial junctions (transitional zones) of the ovary, uterine tube, and stomach. His laboratory established a number of mouse and human organoid systems, thereby allowing parallel ex vivo studies of normal and neoplastic epithelia. Work on those models was essential for development of the concept of stem cell pathology introduced by Dr. Nikitin and colleagues in 2018. Dr. Nikitin's research is complemented by cross-disciplinary collaborations in technology-oriented areas, such as nonlinear microscopy, intravital imaging, nanotechnology, material sciences, and single-cell transcriptomics. Dr. Nikitin is co-organizer of the Annual Workshop on the Pathology of Mouse Models for Human Disease since its inception in 2002.