Special Mouse Strains Resource (SMSR)
Many common inherited human diseases - such as diabetes, cardiovascular disease, obesity, autoimmune disease, and cancer - are genetically complex, resulting from the interaction of more than one gene. Advances in genetic methods and the completed sequencing of the human and mouse genomes make it feasible to detect, genetically map, and identify the genes underlying these complex disorders.
The SMSR is a resource of special strains of mice that are important tools for genetic analysis of such complex diseases. They include panels of recombinant inbred (RI) and chromosome substitution (CS) strains. The primary objective of this project is to make these highly valuable strains available to the scientific community and to enhance their value by additional characterization and curation. The SMSR is funded by a grant from the National Center for Research Resources (NCRR).
