Mutant Mouse Research and Resource Center (MMRRC) at JAX
The Mutant Mouse Research and Resource Center (MMRRC) distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. Previously known as the Mutant Mouse Regional Resource Center, the MMRRC changed its name in 2014 to more accurately reflect the research being done at its regional Repository partners.
Researchers at the MMRRC at JAX Repository are developing pluripotent stem cells from selected MMRRC disease model strains using standard derivation techniques and/or iPS technology. Many studies can be performed in stem cells initially to determine the minimal number of experiments required in live mice.
The MMRRC is a national consortium of breeding and distribution facilities plus an information coordinating center serving together as a NIH-funded repository of spontaneous and induced mutant mouse and cell lines.
The MMRRC is a collaborative effort. Previously funded by the National Center for Research Resources, the MMRRC at JAX is currently supported by the Office of Research Infrastructure Programs/Office of the Director, National Institutes of Health grant number OD010921. Please reference this grant in citations acknowledging use of the resource.