26 Nobel prizes associated with Jackson research, resources and education

George D. Snell of The Jackson Laboratory won the 1980 Nobel Prize in Physiology or Medicine for "discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions."

In fact, 26 Nobel prizes are associated with Jackson Laboratory research, resources and educational programs.
 
Dr. Michael Festing of the Medical Research Council Laboratory of Molecular Biology Toxicology Unit, University of Leicester, England, traced 17 Nobel prizes (awarded before the year 2000), including Dr. Snell’s, to The Jackson Laboratory for an essay, "Mighty Mice," he co-authored with Dr. Elizabeth Fisher, Department of Neurogenetics, Imperial College School of Medicine at St. Mary’s, London. Their essay appeared in the journal Nature, Vol. 404, page 815.

Of the Nobel Prizes awarded after 2000:

  • Richard Axel and Linda Buck, who were awarded the 2004 Nobel Prize, used JAX® Mice in their research into the genetics of the sense of smell.
  • The three Nobel Laureates of 2007 (Mario Capecchi, Martin Evans and Oliver Smithies) also used JAX® Mice in their experiments, which opened the door to genetically modifying mice in order to develop new models for human diseases. 
  • In 1994 The Jackson Laboratory's Dr. John Sundberg collaborated with 2008 Laureate Harald zur Hausen in sequencing the dog oral papillomavirus; this virus and experiments designed by Dr. Sundberg provided the proof of concept for the recombinant human cervical cancer vaccine.
  • 2009 Laureate Jack Szostak began his research career at The Jackson Laboratory's Summer Student Program as a high school student; so did Laureates David Baltimore (1975) and Howard Temin (1975), whose Nobel prizes were counted among those in the Nature essay.
  • Bruce A. Beutler and Ralph M. Steinman each used JAX® Mice in research that earned them both the Nobel Prize in 2011.

1960
Sir Frank Macfarlane Burnet
Walter and Eliza Hall Institute for Medical Research
Melbourne, Australia
For discovery of acquired immunological tolerance

1960
Sir Peter Brian Medawar
University College
London, U.K.
For discovery of acquired immunological tolerance

1975
David Baltimore (member, Jackson Laboratory Board of Trustees; alumnus of Jackson Summer Student Program)
Massachusetts Institute of Technology
Cambridge, Mass.
For discoveries concerning the interaction between tumor viruses and the genetic material of the cell

1975
Howard Martin Temin (alumnus of The Jackson Laboratory's Summer Student Program)
University of Wisconsin
Madison, Wisc.
For discoveries concerning the interaction between tumor viruses and the genetic material of the cell

1980
Baruj Benacerraf
Harvard Medical School
Boston, Mass.
For discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions

1980
George D. Snell
The Jackson Laboratory
Bar Harbor, Maine
For discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions

1984
César Milstein
Medical Research Council Laboratory of Molecular Biology
Cambridge, England
For theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies

1984
Niels K. Jerne
Basel Institute for Immunology
Basel, Switzerland
For theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies

1984
Georges J. F. Köhler
Basel Institute for Immunology
Basel, Switzerland
For theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies

1986
Stanley Cohen
Vanderbilt University School of Medicine
Nashville, Tenn.
For discoveries of growth factors

1986
Rita Levi-Montalcini
Institute of Cell Biology of the College of the Consiglio Nazionale delle Richerche
Rome, Italy
For discoveries of growth factors

1987
Susumu Tonegawa
Massachusetts Institute of Technology
Cambridge, Mass.
For discovery of the genetic principle for generation of antibody diversity

1989
J. Michael Bishop
University of California School of Medicine
San Francisco, Calif.
For discovery of the cellular origin of retrovirus oncogenes

1989
Harold E. Varmus (Honorary Jackson Laboratory Trustee)
University of California School of Medicine
San Francisco, Calif.
For discovery of the cellular origin of retrovirus oncogenes

1996
Peter C. Doherty
St. Jude Children’s Research Hospital
Memphis, Tenn.
For discoveries concerning the specificity of the cell-mediated immune defense

1996
Rolf M. Zinkernagel
Institute of Experimental Immunology
University of Zurich, Switzerland
For discoveries concerning the specificity of the cell-mediaated immune defense

1997
Stanley B. Prusiner
University of California School of Medicine
San Francisco, Calif.
For discovery of prions – a new biological principle of infection

2004
Richard Axel
Columbia University
New York, N.Y.
For discovery of odorant receptors and the organization of the olfactory system

2004
Linda Buck
Fred Hutchinson Cancer Research Center
Seattle, Wash.
For discovery of odorant receptors and the organization of the olfactory system

2007
Mario R. Capecchi
Howard Hughes Medical Institute
University of Utah
Salt Lake City
For discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells

2007
Sir Martin J. Evans
Cardiff University
Cardiff, U.K.
For discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells

2007
Oliver Smithies
University of North Carolina at Chapel Hill
Chapel Hill, N.C.
For discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells

2008
Harald zur Hausen
German Cancer Research Centre
Heidelberg, Germany
For discovery of human papilloma viruses causing cervical cancer

2009
Jack W. Szostak (alumnus of The Jackson Laboratory's Summer Student Program)
Howard Hughes Medical Institute
Harvard Medical School and Massachusetts General Hospital
Boston, Massachusetts
For the discovery of how chromosomes are protected by telomeres and the enzyme telomerase

2011
Bruce A. Beutler
The Scripps Research Institute
La Jolla, Calif.
For discovery concerning the activation of innate immunity

2011
Ralph M. Steinman
Rockefeller University
For discovery of the dendritic cell and its role in adaptive immunity