22 Nobel prizes associated with Jackson research and resources
Fifteen researchers won Nobel Prizes in Medicine or Physiology for research using inbred mice developed at The Jackson Laboratory. Six others employed genetic principles first developed by C.C. Little, founder of The Jackson Laboratory.
Dr. Michael Festing of the Medical Research Council Laboratory of Molecular Biology Toxicology Unit, University of Leicester, England, traced 17 of the Nobel prizes (those awarded before the year 2000) to The Jackson Laboratory for an essay, "Mighty Mice," he co-authored with Dr. Elizabeth Fisher, Department of Neurogenetics, Imperial College School of Medicine at St. Mary’s, London. Their essay appeared in the journal Nature, Vol. 404, page 815.
The three Nobel Laureates of 2007 (Mario Capecchi, Martin Evans and Oliver Smithies) also used JAX® Mice in their experiments, which opened the door to genetically modifying mice in order to develop new models for human diseases.
In 1994 The Jackson Laboratory's Dr. John Sundberg collaborated with 2008 Laureate Harald zur Hausen in sequencing the dog oral papillomavirus; this virus and experiments designed by Dr. Sundberg provided the proof of concept for the recombinant human cervical cancer vaccine.
1960
Sir Frank Macfarlane Burnet
Walter and Eliza Hall Institute for Medical Research
Melbourne, Australia
For discovery of acquired immunological tolerance
1960
Sir Peter Brian Medawar
University College
London, U.K.
For discovery of acquired immunological tolerance
1975
David Baltimore (member, Jackson Laboratory Board of Trustees; alumnus of Jackson Summer Student Program)
Massachusetts Institute of Technology
Cambridge, Mass.
For discoveries concerning the interaction between tumor viruses and the genetic material of the cell
1975
Howard Martin Temin (alumnus of The Jackson Laboratory's Summer Student Program)
University of Wisconsin
Madison, Wisc.
For discoveries concerning the interaction between tumor viruses and the genetic material of the cell
1980
Baruj Benacerraf
Harvard Medical School
Boston, Mass.
For discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions
1980
George D. Snell
The Jackson Laboratory
Bar Harbor, Maine
For discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions
1984
César Milstein
Medical Research Council Laboratory of Molecular Biology
Cambridge, England
For theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies
1984
Niels K. Jerne
Basel Institute for Immunology
Basel, Switzerland
For theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies
1984
Georges J. F. Köhler
Basel Institute for Immunology
Basel, Switzerland
For theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies
1986
Stanley Cohen
Vanderbilt University School of Medicine
Nashville, Tenn.
For discoveries of growth factors
1986
Rita Levi-Montalcini
Institute of Cell Biology of the College of the Consiglio Nazionale delle Richerche
Rome, Italy
For discoveries of growth factors
1987
Susumu Tonegawa
Massachusetts Institute of Technology
Cambridge, Mass.
For discovery of the genetic principle for generation of antibody diversity
1989
J. Michael Bishop
University of California School of Medicine
San Francisco, Calif.
For discovery of the cellular origin of retrovirus oncogenes
1989
Harold E. Varmus (Honorary Jackson Laboratory Trustee)
University of California School of Medicine
San Francisco, Calif.
For discovery of the cellular origin of retrovirus oncogenes
1996
Peter C. Doherty
St. Jude Children’s Research Hospital
Memphis, Tenn.
For discoveries concerning the specificity of the cell-mediated immune defense
1996
Rolf M. Zinkernagel
Institute of Experimental Immunology
University of Zurich, Switzerland
For discoveries concerning the specificity of the cell-mediaated immune defense
1997
Stanley B. Prusiner
University of California School of Medicine
San Francisco, Calif.
For discovery of prions – a new biological principle of infection
2007
Mario R. Capecchi
Howard Hughes Medical Institute
University of Utah
Salt Lake City
For discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells
2007
Sir Martin J. Evans
Cardiff University
Cardiff, U.K.
For discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells
2007
Oliver Smithies
University of North Carolina at Chapel Hill
Chapel Hill, N.C.
For discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells
2008
Harald zur Hausen
German Cancer Research Centre
Heidelberg, Germany
For discovery of human papilloma viruses causing cervical cancer
2009
Jack W. Szostak
Howard Hughes Medical Institute
Harvard Medical School and Massachusetts General Hospital
Boston, Massachusetts
For the discovery of how chromosomes are protected by telomeres and the enzyme telomerase
