Searchable Database
Notes About IMR Strains
If you are searching for a specific transgenic line, it may be best to search under "Mutation Symbol" first; if you do not find it there, search in the "Gene Locus/Symbol" field.
To verify that you are using the correct gene symbol, please check in the Mouse Genome Database.
If you have problems searching the database, please contact the IMR Database Administrator.
Strains are listed alphabetically by gene within mutation type categories (Chemically induced, KO (homologous recombination), Retroviral Insertion, or Transgenic). Some gene names are truncated on the indexed list, but appear in full in the subsequent reference list.Availability Levels - Definitions of the terms:
Accepted Not Yet Available
Accepted by the Genetic Resources Committee for importation, but has not yet arrived or has not yet passed importation.
Once a strain arrives in the Importation Facility at The Jackson Laboratory, it is listed on this web site.
Please indicate your interest in this strain by casting your vote. Monthly reviews of this list help us determine the size of the colony. The median time to level 4 distribution (Available as breeder pairs or individual mice) is 7 months after a strain arrives in our Importation Facility. Circumstances such as the number of animals we initially receive for the hysterectomy derivation process, the genotype of the animals and how well they breed in isolators determines the actual time to reach distribution. In rare instances this may be longer than 7 months.
(1) Generally available in quantities greater than 25. Shipment date is usually given when an order is placed.
(2) Generally available in quantities up to 25. Please call to discuss larger orders. Estimated shipment date is given when an order is placed.
(3) Generally available in quantities of 2 - 10. Please call to discuss larger orders. Estimated shipment date is given when an order is placed.
(4) Available as breeder pairs or individual mice. Please call to discuss larger orders. Estimated shipment date is given when an order is placed.
(5) Cryopreserved. Provided as 2 litters or up to 3 breeding pairs after recovery of about 6 months. Additional repository fee required (see page 153 of the 1998 Price List and Product Guide). Call for genotype.
Note: In any of the last three categories there may be some wait for mice if they require testing or can not be held in inventory due to early lethality.
Nomenclature
For transgenic strains, the nomenclature, if complete, is correct. Italics should not be used in transgenic nomenclature. There are incomplete symbols for some strains. They may be lacking an assigned number and/or a laboratory registration code, designated by the "#" symbol. These symbols are provisional until the genetic nomenclature is completed and approved. Please inquire about the proper symbols before using these in a publication.
Recently a revision has been made to the nomenclature.
The designation of STOCK as a genetic background will largely be replaced by more specific nomenclature. A comma separating two strain abbreviations in a strain symbol, e.g. B6,129, indicates an inbred strain maintained by sibling matings and composed of genetic background from only the two inbred strains indicated. It is not necessarily constructed from F2 matings as is a recombinant inbred strain. The order of the strains in the symbol has no significance; B6, when involved, will be written first for consistency.
References
Some entries do not have complete references because the manuscript is in preparation.
Congenic Strains
Where the strain is indicated as C57BL/6J, the generation number may be as low as N=5. If you need more information on the genetics of congenics, please contact Customer Service at 1-800-422-MICE.
