The FaceBase Mouse Resource for Orofacial Clefting Research at JAX
Principal Investigators: Leah Rae Donahue, Steve Murray
The FaceBase Mouse Resource at JAX is a comprehensive mouse resource to facilitate research on orofacial clefting. The Repository provides services and mouse resources to the Facebase consortium, as well as to the greater research community. First, in close coordination with the Facebase consortium, the FaceBase Resource is generating new inducible Cre driver lines specifically designed to support orofacial clefting research. Second, the FaceBase Resource provides a repository for rederivation, cryopreservation, genetic quality control, and distribution of live colonies of new and existing mouse models and tool strains relevant to orofacial clefting research.
Researchers who would like to share their orofacial mouse models with the scientific community are encouraged to donate a strain to the repository.
The Genetic Resource Science group at JAX, responsible for the FaceBase Resource, has more than fifty years of repository colony management experience plus The Jackson Laboratory’s strengths in providing customer support, high animal health status, informatics, and efficient distribution of mice. Together these projects provide Facebase members and the scientific community with mouse services, tools, and new models to further research in orofacial clefting.
The FaceBase Resource at JAX and the FaceBase Consortium is funded by the National Institute of Dental and Craniofacial Research (NIDCR) grant number DE20052. Please reference this grant in citations acknowledging use of the resource.
