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Alström Syndrome is a hereditary, recessive syndrome. It can be inherited by both males and females with equal probability.

A person who has Alström Syndrome must have inherited two copies of the mutated gene, one from each parent.

Each parent of an affected child carries only one copy of the gene and unknowingly passes it to their offspring. In the case of Alström Syndrome, there are no visible symptoms of the disease in an individual who carries only one copy of the gene.

Although this does not happen in every case, the statistical probability with each pregnancy from two individual carriers is:

  • 1 chance in 4 that the child will have no copies of the mutation, thus not be a "carrier"

  • 2 chances in 4 that the child will inherit only one copy of the gene, thus the child would be a "carrier"...

  • 1 chance in 4 that the child will inherit two copies of the gene, one from each parent, and thus be affected with Alström Syndrome.

Mode of Inheritance Diagram

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Last Modified: June 23, 2008